All participants will be asked to:

* Read & evaluate a consent form

* Complete a questionnaire

* Donate a blood sample (approx. 60mL: about 1/5 of a Red Cross donation unit)

* Donate a saliva sample (approximately 2mL)

* If a joint is acutely inflamed, a study participant may be asked to undergo arthrocentesis, a brief procedure to sample joint fluid (synovial fluid).


Patient participation requires a phone interview with our staff regarding the history of chikungunya infection, other past medical history, family history, travel history, and requesting of medical records by the study from the participant's doctors.


All patient samples are confidential. Your questionnaire and samples will be stripped of any identifying information, such as your name and personal information, meaning that they will be de-identified. No one will have direct knowledge of your health and related information except for the person collecting the information and selected laboratory personnel.


Qualifying for Study Participation

Not everyone who volunteers to participate will qualify for many different reasons. However, we will contact you regarding your status in the study. You may also contact us at any time by email:


What is Done with Your Blood Sample

First, any identifying information associated with the blood sample will be stripped, meaning the samples will be de-identified. If any tests are run on the sample, these results cannot be given to the participant since the samples will have been de-identified and we will not be able to correlate sample results with the name of any donor.

A group of tests important for evaluating Chikungunya infection will be performed on the samples.


DNA from saliva will be analyzed to determine which genes may be involved in vulnerability to Chikungunya infection and to address other scientific questions as they arise.


Some blood cells will be stored for use in future Chikungunya research.


If you participate in the study, a recruiter will answer all your questions and help you review the paperwork.  We will also arrange a time for your sample donation.


Potential Risks

There are small risks associated with donation of blood:

* Bruising can occur at the point of withdrawal.

* Rarely, a person may experience fatigue, dizziness, or fainting

* Very rarely, infection can occur.

* For patients who undergo arthrocentesis, there is a very rare incidence of serious joint infection (less than 1 in 15,000 risk).


Benefits of Participation

There are no direct benefits to participants


Every participant will contribute to a team of doctors, nurses, scientists, and staff who are all trying to understanding Chikungunya virus and important, unanswered questions including why some patients develop chronic symptoms and others develop no symptoms at all.

A Brief Overview for Participants

If you are interested in participating in research to help address these issues, email a recruiter at or call 1-314-747-4179.


Please only provide very basic contact information in your  initial email.  When we receive your message, we will reply with instructions for secure email communication.







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